Vet Comp Orthop Traumatol 1988; 01(02): 74-79
DOI: 10.1055/s-0038-1633168
Short Communication
Schattauer GmbH

Polymethylmethacrylate: a Review of the Implications and Complications of its Use in Orthopaedic Surgery

G. I. Anderson
1   From the Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario NIG 2W1
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Publikationsdatum:
22. Februar 2018 (online)

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Polymethylmethacrylate has application in the fixation of endoprostheses and void-filling in reconstructive and neurological surgery in both veterinary and human surgery. It also has extensive dental and ophthalmic applications. Literature detailing the nature of the bone/cement interface is reviewed along with the local effect of polymethylmethacrylate on bone and cartilage. The repercussions of the cellular effects of polymethylmethacrylate on the development of loosening are discussed. The immunosuppressive effects of polymethylmethacrylate to the patient are outlined. A review of the cardiovascular, pulmonary and hepatic toxicity problems of polymethylmethacrylate is included. Contact sensitisation of the user is briefly discussed in conclusion.